Welcome

www.PlantSphingolipids.org

Welcome to the lab website for Dr Jonathan E. Markham at the Department of Biochemistry, University of Nebraska-Lincoln. This website is a resource for information on plant sphingolipids as well as other areas of instruction and research being carried out in Dr Markham's lab.

Research in the Markham lab is focused on understanding the organization of (sphingo)lipid metabolism and how metabolic components of this pathway can influence critical cell-fate decisions. Our philosophy is that in order to be able to understand how metabolites are involved in metabolic and physiological life processes, one must be able to measure them - seeing is believing! We use the latest tools in biochemistry - mass spectrometry - to measure many molecules involved in plant sphingolipid biochemistry including – but not limited to – fatty acids, steroids, amino acids, sphingolipids, glycerolipids, nucleotide phosphates and UDP/GDP-sugars. By obtaining accurate measurements of these molecules in different genetic backgrounds, we are able to piece together how the different structures contribute towards sphingolipid biochemistry, cellular signalling and plant physiology.

Below you will find further information about plant sphingolipids, our research and activities in the Markham lab.

Contact Dr. Markham
Email: ude.lnu|mahkramej#ude.lnu|mahkramej
Tel: (+1) 402 472-6967
Campus: N146 Beadle Center, 1901 Vine St, Lincoln, NE 68588


Information and Resources

Sphingolipids

Information on the structure, detection and function of plant sphingolipids and just what makes them so enigmantic.

sphinx_greek.jpg

The Riddle of the Sphinx
(as relates to sphingolipids):


What contains long acyl-chains like a lipid, but cannot be saponified by mild base and is soluble in aqueous-solvents?

Lipid metabolism


Lipidomics


Membrane Biogenesis


Educational Materials

Latest Papers

Google Scholar Citations

PubMed links by date

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Lab organization

Positions Available

Job openings available in the Markham Lab

Current Projects

A description of current research projects and collaborations being carried out in the lab.


Lab Members


Lab Equipment


Protocols

Unless otherwise stated, the content of this page is licensed under Creative Commons Attribution-ShareAlike 3.0 License